FDA warns about dental problems associated with buprenorphine medications

In early January 2022, FDA released a Drug Safety Communication surrounding dental problems following use of buccal and sublingual buprenorphine products for the treatment pain opioid disorder. The warning comes after reports problems, including tooth decay, cavities, oral infections, loss teeth, in patients using buprenorphine, regardless their history. Buprenorphine variety formulations, Subutex (sublingual tablets); Suboxone (combination product with naloxone available both films Sublocade (extended-release subcutaneous injection); Belbuca (buccal film); Butrans (transdermal patch). Initially approved disorder 2002 as tablet, were later pain. (buprenorphine transdermal patches) are currently only FDA-approved management severe enough to require daily, around-the-clock, long-term which alternative options inadequate. Opioid agonist medications, can reduce saliva production mouth, according FDA. Reduced lead mentioned previously. While or injectable formulations have risk dry these not statement. said they will be requiring new on added prescribing information patient medication guides all dissolvable containing products. This is required patch formulations. With this warning, recommends prescribers, dentists, pharmacists do part educating health. Prescribers should prepared ask about health history, last time was seen by dentist. Also, may also recommendations dentists whom refer patients. addition informing proper hygiene techniques, counsel gently rinse teeth gums water, then swallow once has completely dissolved. They need wait at least one hour taking dose before brush teeth. Some steps that take optimum decay include twice daily brushing, regular flossing, drinking water throughout day, routine checkups. Substance Abuse Mental Health Services Association “[urge] providers weigh lifesaving benefits identified making decisions starting ongoing buprenorphine.” states when combined counseling other behavioral therapies, commonly most effective way treat